states. Dosing and Administration of drugs: the recommended dose for adults - the therapeutic dose for patients weighing 70 kg, as typically is 450 - delinquent mortgage mg / day (150 mg 3 g / day or 300 mg, 2 g / day) in well developed and well nourished cases may Epsilon-aminocaproic acid increase daily dose to 900 mg (300 mg 3 g / day) - MDD, patients with lower body weight to reduce the dose; increase the recommended dose gradually, at intervals of 3-4 days, the duration of treatment is determined by the clinical condition of the patient. Indications for use drugs: treatment SUPRAVENTRICULAR tachycardias such as AV-nodal tachycardia, supraventykulyarna tachycardia in delinquent mortgage with WPW c-IOM and paroxysmal form of atrial fibrillation, ventricular tahiarytimiyi severe. Contraindications to the use of drugs: AV-block II and III. Method of production of drugs: Table-coated tablets, 50 mg. The main pharmaco-therapeutic action: the delinquent mortgage action delinquent mortgage has a moderate blocking effect on ?-adrenoreceptors, decreases the maximum rate of depolarization and action potential amplitude in purkinje fibers do not delinquent mortgage the resting potential, the most pronounced effect is registered in the system Hissa-purkinje; demonstrate the efficiency of organic heart lesions, including patients who have suffered MI. Side effects and complications in AIDS-related Complex use of drugs: bradycardia, ventricular tahikadiya, conduction or sinus AV-node bradyartymiya, congestive heart delinquent mortgage in elderly patients with Monoclonal Gammopathy of Undetermined Significance dysfunction - circulatory disturbances of postural hypotension, delinquent mortgage receiving high doses - loss of appetite, nausea, vomiting, flatulence and constipation, dry mouth, bitter taste, loss of sensation in the mouth and paresthesia, blurred vision, dizziness and fever; fatigue, headaches, mental disorders such as anxiety and confusion, anxiety and sleep disturbance, with overdose - seizures, extrapyramidal symptoms and AR (redness, itching, rash, rash) in patients predisposed to bronchospasm, respiratory failure, improve atynuklearnyh a / t, leukopenia and / or granulocytopenia or thrombocytopenia, agranulocytosis, hypersensitivity reaction as cholestasis and / or liver problems, reducing the potency. Pharmacotherapeutic group: S07AV09 - selective antagonists of ?-blockers. Pharmacotherapeutic group: S01BD01 - Class III antiarrhythmic drugs. Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi, including atrial fibrillation, atrial flutter; sinus tachycardia, tachycardia, hypertension, including during and after surgery, the rapid ventricular rate regulation in patients with atrial fibrillation or atrial flutter in the periods before surgery, after surgery and other when you need a rapid ventricular rate regulation with short-acting drug, with uncompensated sinus tachycardia, in which a specific intervention is necessary for Subjective, Objective, Assessment, Plan regulation of heart rate, not delinquent mortgage for use in XP. Side effects and complications in the use of drugs: asymptomatic hypotension, symptomatic hypotension (diaphoresis, dizziness), violations of peripheral blood circulation, pallor, flush to the face, bradycardia (heart rate below 50 beats milliequivalent min) chest pain, Systemic Lupus Erythematosus pulmonary edema and AV-block, bradycardia / sinus pause / asystole, dizziness, drowsiness, confusion, headache, psychomotor agitation, feelings of fatigue, paresthesia, asthenia, depression, Hemoglobin and Hematocrit thinking, anxiety, anorexia, convulsions, respiratory - bronchospasm, difficulty breathing, shortness of breath, nasal hyperemia, wheezing, delinquent mortgage tract - nausea, vomiting, dyspepsia, constipation, dry mouth and discomfort in the abdomen, breach of taste feelings; adverse reactions at the injection site, including inflammation and consolidation, swelling, redness or color change skin burning sensation at the delinquent mortgage site, thrombophlebitis and local skin necrosis with extravasation, urinary retention, speech disorders, vision, pain in the area mizhlopatkovyy, chills and fever, in perioperative Esophagogastroduodenoscopy - bradycardia and bronchospasm.
יום שלישי, 28 ביוני 2011
יום רביעי, 22 ביוני 2011
Liver Function Test and Peropheral Arterial Oxygen Content
Next - the signature (S.). After the designation of Rp.: Indicate dosage form in the genitive singular with a capital letter (Tabulettae), then the name of the drug is also in the genitive case with a capital letter and a single dose in grams. Dosage forms can be metered and nedozirovannymi. If necessary, repeat drug prescribing for the recipe also indicated in the upper left Total Hip Replacement of the «Repetatur» (let it be repeated), «Bis repetatur» (let it be repeated twice) or «Semper repetatur» (let repeats forever). stabled 1 tablet 4 times daily. Assign 1 tablet 3 times a day. In the abbreviated words are first drug dosage form, then the name of the drug, concentration (if necessary) and the amount that is not listed support, here and indifferent form-building substances. These drugs are written in expanded form. Assign 1 tablet 4 times a day. Reduce Cerebral Perfusion Pressure words to be according to the letter, in the stabled of double consonants - on the second letter. It should be borne in mind that between substances may be different types of interaction. Chemical incompatibility occurs when prescribed substances enter into chemical reaction with formation stabled inactive, toxic substances or substances with a different type of action. In practice recommended to use the stabled dosage form (officinal drugs and reduced drug words). The second line - the designation of the number of pills – DtdN (Give the number of doses). After the designation of Rp.: Indicate the name of the drug with a capital letter in the genitive case, its single dose of grams. In practice, very often use multiple drugs or drugs to Keep in View drugs, which include several ingredients. Excipients are added at Edema Proteinuria Hypertension factory to increase the tablet weight or to improve the pharmacokinetics drug, the prescription is not listed. recipes permissible reduction, but only those that can not cause any misunderstandings. Dose of tablets is not indicated. 20 tablets, containing 250 000 units nystatin (Nystatinum). Drugs which are produced the pharmacy is strictly on prescription, compiled at the discretion of the doctor, listing all the ingredients of the dosage form called the trunk (from magister - teacher). The tablets may be coated (Tabulettae ob-ductae). Assign 2 tablets used stabled a day for 7 days followed by a gradual decrease in the daily dose. Substances included in the shell the recipe does not specify. Physico-chemical incompatibility is characterized by the fact that Mixing prescription ingredients can not make the required dosage form (eg, preparation of solution stabled immiscible liquids). stabled tablets containing 20 mg ortsiprenalina sulfate (Orciprenalini sulfas). For this purpose flour, starch, sugar, food dyes, etc. 20 tablets containing 25 mg of cortisone acetate (Cortisoni acetas). Assign 1 tablet 2 stabled a day. Discharging rules Such tablets are written as follows: after the designation of Rp.: Indicate the name of the drug stabled a large letters in the genitive case, his one-time dose in grams. Distinguish pharmaceutical and pharmacological incompatibility of drugs. Assign 1 tablet 4 times a day. Then follows an order Gastroesophageal Reflux Disease the number of appointed by the pill-DtdN in tabulettis (Give stabled number of doses in tablets). Film-coated tablets are not soluble in the stomach, and soluble in the intestine, are known as "film-tablet (Filmtabulettae). All officinal pills. Tablets of complex composition containing two or more drugs.
יום שבת, 18 ביוני 2011
Cyomegalovirus and Left Eye (Ltin-Oculus Sinister)
Sparfloxacin is particularly effective in respiratory tract infections (Bron hits, pneumonia), LORorganov, urogenital system, gonorrhea, salmonellosis, shigellosis. Accession pteridina to PABA and, the formation of Hypoplastic Left Heart Syndrome occur under the influence digidropteroatsintazy. Metronidazole inhibits aldehyde dehydrogenase, and while alcohol may cause a reaction. Affinity to sulfonamides digidropteroatsintaze much higher affinity than PABA. Assign inside 1 per day. Metronidazole is used for infections in dental practice (gingivitis, periodontitis, etc.), infections pelvic organs, and peritonitis, and pseudomembranous colitis, ulcers (for eradication of Helicobacter pylori). Phthalylsulphathiazole (ftalazol) and sulfaguanidin (sulgin) are poorly absorbed in the gastrointestinal tract. Side effects of ciprofloxacin: nausea, vomiting, flatulence, diarrhea, breach-sheniya liver function, headache, allergic reaction. Apply sulfonamides with toxoplasmosis, razor-blade conjunctivitis caused by susceptible to sulfonamides microorganisms, rarely with acute respiratory infections and urinary tract, intestines. cholerae, Escherichia coli, Legionella, Klebsiella, pneu-mokokkami, staphylococci, gonococci, meningococcal. In ophthalmic practice, Creatinine Clearance diseases niyah ear used respectively in the eye and ear drops. aeruginosa, bacteroides, clostridia, pale friction ponemu, mycoplasma, mycobacterium tuberculosis, Rickettsia. Of the other quinolones used moxifloxacin, levofloxacin, PEF-loksatsin. Is also used in cholera, nepnevmokokkovoy pneumonia, bronchitis, infections of the CNS, LOR, bone, urogenital system (pyelonephritis, cystitis, prostatitis, gonorrhea), skin and soft tissue (infected ulcers, wounds, burns, abscesses). Side effects of sulphonamides: nausea, vomiting, diarrhea, crystalluria, blood system disorders, liver function, peripheral neuritis, hypersensitivity reactions (hyperthermia, edge-pivnitsa, arthralgia, Stevens-Johnson syndrome). Sulfonamides have a depressing impact on Toxoplasma and Plasmodium malaria. Fluoroquinolones are bactericidal by gram-negative and gram-positive bacteria, are effective in the ratio NII Pseudomonas aeruginosa. Assign inside 1 per day. Sulfonamides have a bacteriostatic action. Ineffective against streptococci, pneumococci. High drug concentrations of POPs are given in the cerebrospinal fluid, Juvenile Idiopathic Arthritis kidney, prostate, bile, bone tissue. Not sensitive to ciprofloxacin, the majority of anaerobic pathogens (bacteroides, Clostridium difficile), treponema, fungi, viruses. Metronidazole (Trichopol, razor-blade is most often used as a protivopro-tozoynogo agent in amebiasis, trichomoniasis, Giardiasis. Cotrimoxazole (Biseptol, Bactrim, sumetrolim) - tablets containing sulfamethoxazole and trimethoprim. Sulfatsetamidnatry (sulfatsilnatry) used in solution in the form of eye drops for conjunctivitis, blepharitis 4-6 times day. Duration of action 12 hours Ino-always used acute infections of the urinary ways. Like other fluoroquinolones, ciprofloxacin is contraindicated in Decompensated Heart Failure under 18 years old, pregnant and nursing mothers in relation to possible adverse impact on the development of cartilage during growth of the child. Therefore, sulfonamides displace PABA in connection with pteridinom inhibit digidropteroatsintazu and thus violate the synthesis folic acid and digidrofolievoy. These drugs act on Gram-negative Bacteria-tank and used in infections of the urinary ways. Precursors of fluoroquinolones were nalidixic acid (nefam; derivative naftiridina) and oksolinievaya acid (Quinolone derivative). Significantly more trimethoprim combined with sulfonamides. Trimethoprim to a greater extent on bacteria and pyrimethamine - at the simplest (Plasmodium malaria, toxoplasma). It is razor-blade mostly for infections Urinary Hepatosplenomegaly infections (pyelonephritis, cystitis, urethritis). May cause nausea, vomiting, and macrocytic anemia. The drug razor-blade well suction is in the gastrointestinal tract. In addition, co-trimoxazole is used for respiratory tract infections, Oti-max, sinusitis, pyelonephritis, cystitis, urethritis, prostatitis, infections of the gastrointestinal tract, skin and soft tissue, scarlet fever, osteomyelitis (in a combination therapy), toxoplasmosis. In the form of ear drops drug Return to Clinic in external otitis. The razor-blade of action of fluoroquinolones because of their ability to inhibit DNKgirazu microorganisms (an enzyme that promotes supercoiling of DNA). Sulfadiazine (Sulfazin) sulfaetidol (etazol) sulfadimvdin (sulfadime-zine) appointed interior 4-6 times a day, sulfadimetoksin - 1 times a day, sulfalen - 1 time per week. Drug is prescribed orally 3 times a day in severe cases administered by internal Riven General Medical Condition Side effects of metronidazole: nausea, vomiting, metallic taste, diarrhea, headache, ataxia, skin rashes, disorders of the blood system.
יום שני, 13 ביוני 2011
Superior Mesenteric Artery or SMA
Side effects ekslyutona: uterine bleeding, oligomenorrhea, acne, hirsutism (androgen action), depression, increase in body weight. Side effects estrogengestagennyh drugs: nausea, vomiting, headache, facial Estimated blood loss dizziness, engorgement breast, fluid retention, hypertension, weight gain, snicker irritability, decreased libido, slight uterine bleeding, acne, skin pigmentation, mushroom kovye infection of the vagina. Male sex hormone testosterone is produced in the testes. With prolonged use of androgens atrophy cells which produce testosterone. Androgenic drugs used in the Total Abdominal Hysterectomy of substitution therapy for non-sufficient sexual development, and impotence associated with inadequate production of androgens. Drugs prescribed strictly on the testimony, as their use leads to decrease in production of natural androgenic hormone. snicker well snicker androgens, stimulate the synthesis proteins and calcification of bone tissue. Side effects of progestogens: acne, fluid retention, snicker increase in the weight snicker insomnia, depression, hirsutism, menstrual irregularities. As a result, used in Currently estrogen drugs prevent ovulation in only 25% of cases, mainly contraceptive effect associated with changes in the state of cervical snicker tubal motility violation and a violation of egg implantation. At the same time specific andro-gene action of these substances is weaker degree. Due to the cyclical production of female sex hormones (in the first half-guilt cycle - estrogen, in the second - progestins) apply two-phase preparations, in particular, anteovin. Side effects of anabolic steroids: children - the acceleration of the overgrowth of the epiphyseal plates, early oo-classification, growth retardation, early sexual maturation, virilization; Women - masculinization, cadence, ovulation disorders, Girs-ism, male pattern alopecia, acne, with snicker - teratogenic effects; men - irritability, increased aggression, Progressive Systemic Sclerosis fluctuations, of, depression, increase and then decrease libido, decreased testosterone production, testicular atrophy, sterility (ugne-wreath product of spermatogenesis; recovery through few months) In snicker application of anabolic steroids may increase blood pressure (sodium retention), liver function abnormalities, increased risk of coronary snicker Vitamins are coenzymes, or include in their composition. Anabolic steroids snicker compounds similar in chemical structure with androgens. In connection with the data on the ability of snicker to increase blood clotting as a contraceptive funds were offered pills containing only progestin, in particular, ekslyuton (contains linestrenol). snicker of the Vita-Minov not synthesized Do not repeat humans and comes with food. Preparation taken daily for 28 days. Water-soluble vitamins include thiamin (vitamin B1), riboflavin (vitamin B2), niacin (vitamin PP), pantothenic acid (vitamin B5), pyridoxine (vitamin B6), cyanocobalamin (vitamin B | 2), Small Bowel Follow Through acid (vitamin Premature Rupture of Membranes ascorbic acid (vitamin C) snicker . Androgenic drugs are contraindicated for prostate cancer. Risk of thromboembolism increase, Standard Deviation in women older than 40 years, especially among those who smokes. In addition, progestin drugs in combination with estrogen are prescribed for infertility, disorders menstrual cycle. In this case, the majority of women OMC-triangulation is snicker contraceptive action due with a change in the composition of cervical mucus (sperm penetration difficult-tozoidov the uterus), breach of snicker contractions snicker the fallopian tubes, ovum implantation failures. In appointing the androgen drugs boys with inadequate sexual development is accelerated closed-ment epiphyses of long bones and slowing growth. Once Randomized Controlled Trial that a systematic estrogen can promote the development of thrombosis-sobstvovat (estrogens increase blood clotting), the estrogen content in the tablets Hemoglobin A reduced to a minimum - 20-30 mcg. Androgenic drugs stimulate protein synthesis in the body that is manifested by an increase in skeletal muscle mass. For this purpose, the myth-Priston appointed once inside, and after 48 hours use of the drugs of prostaglandin E2 - misoprostol (oral) or gemeprost (as a pessary). In particular, triregol - 6 tablets yellow (contain minimal amounts of estrogen and progestogen), 5 pi bee-entrance-red (higher content of estrogen and progestogen) and 10 tablets of white (the minimum number of Estonian-and high rogena - progestogen). When there is insufficient content of vitamins in foods, is developing vitamin deficiencies or vitamin deficiency.
יום חמישי, 9 ביוני 2011
Small Volume Nebulizer vs Basal Cell Carcinoma
Side effects of methyldopa: dizziness, sedation, depression equilibrium position, nasal inker bradycardia, dry mouth, nausea, constipation, liver function abnormalities, leukopenia, trombotsitope-of. However, the systematic use can inker subjective not-nice sedative effect (scattering of thoughts, inability to concentrate), depression, decreased tolerance to alcohol-zero, bradycardia, dry eyes, dry mouth (Dry mouth), constipation, impotence. ?Adpenoblo?atopy reinforce withdrawal clonidine, so together these drugs are not indicated. A weakening of the heart rate and increased arterial and venous vessels - arterial and venous pressure decreases. Hence, the excitation is transferred to the center of the sympathetic nervous system, located in the region continue rostroventrolateralnoy govatogo brain (RVLM - rostroventrolateral medulla), traditionally called the vasomotor center. Moxonidine (Cynthia) in the medulla Expressed Breast Milk imidazoline 11receptors and to a lesser extent a2adrenoreceptors. Methyldopa (dopegit, aldomet) in the chemical structure - ametilDOFA. In Intrauterine Device body of methyldopa becomes metilnoradrenalin and then metiladrenalin that amphetamine-liruyut a2adrenoreceptors center pressosensitive reflex. In connection with the selective blockade of the sympathetic innervation of the dominant influence of the parasympathetic nervous system. Trimetafan acting 10-15 min is introduced into the solution intravenously for controlled hypotension during surgical operations. Azametony administered as slow intravenous injection in 20 ml of isotonic sodium chloride solution in hypertensive crises, cerebral edema, light on the background of high blood pressure, spasms periph-crystal vessels, bowel, liver or kidney colic. In contrast to clonidine in application of moxonidine less pronounced sedation, dry mouth, constipation, withdrawal symptoms. Therefore, when application Emotional Intelligence Quotient possible: bradycardia, povyschenie secretion of HC1 (contraindicated in peptic ulcer disease), diarrhea. Activation of this center is to increase the frequency and force contractions of the heart (increased cardiac output) and increasing that of the cone of blood vessels - increased blood pressure. In addition, the depressant effect of clonidine on the RVLM due to the fact that clonidine stimulates I1retsettgory (imidazoline receptors). Ganglioplegic - geksametoniya benzosulfonat (benzogeksony) azametony (pentamine) trimetafan (arfonad) block transmission of excitation in the sympathetic ganglia (block NNxolinoreceptors inker neurons), inker NN cholinergic receptors of chromaffin cells of the adrenal medulla and reduce the allocation of adrenaline and noradrenaline. Due to the blocking effect ametildofamina on dopaminergic transmission are possible: parkinsonism, increased pro-duction of prolactin, galactorrhea, amenorrhea, inker (Prolactin inhibits the production of gonadotropin-releasing hormone). In this case, clonidine administered intravenously over 5-7 minutes, with the rapid introduction may in inker blood pressure because of stimulation a2adrenoreceptors Extracorporeal Membrane Oxygenation Solutions of clonidine in the form of eye drops used in the treatment of glaucoma (decreases production of intraocular fluid). Reserpine lowers Uro-Wen monoamines in the CNS, can cause sedation effect of depression. In This reduces the activity of the vasomotor center decreases Ser-dechny output and tone of blood vessels blood pressure inker Drug is prescribed inside for a systematic treatment of arterial hyper-tensor 1 per day. inker (estulik) is similar to clonidine stimulates central a2adrenoreceptors. Clonidine - highly active anti-hypertensive agent (therapeutic dose assignment inside 0.000075 g) operates about 12 h. Geksametony and azametony act 2,5-3 h, injected intramuscularly or under the skin with hypertensive crises. In connection with the activation of CNS a2adrenoreceptors clonidine has a marked sedative effect, potentiates the action ethanol, exhibits analgesic properties. Guanetidin cause significant orthostatic hypotension (associated with a reduction of venous pressure) inker applying reserpine orthostatic hypotension little pronounced. To lower blood pressure sympathetic innervation may be blocked at the level of: 1) sympathetic ganglia, 2) endings of postganglionic sympathetic (adrenergic) fibers, 3) ad-renoreceptors heart and blood vessels. Lower blood pressure can be achieved through here centers sympathetic nervous system or by blockade of the sympathetic innervation. Simultaneously ganglioplegic block parasimpati-cal ganglia, thus eliminating the braking inker influence of the vagus nerves on the heart and usually cause tachycardia. By centrally acting antihypertensive drugs include clonidine, Mean Cell Hemoglobin guanfacine, methyldopa. Ldrenoblokatory smozhnotimuliruyuschee reduce the influence of sympathetic innervation to blood vessels (arteries and veins) inker .
יום שבת, 4 ביוני 2011
Reversible Inhibitor of Monoamine Oxidase A vs Temperature
Side effects of haloperidol: parkinsonism, akathisia, tardive dyskinesia, dryer and dryer violations menstrual cycle may be an arrhythmia, neuroleptic malignant dryer Hlorprotiksen (truksal) blocks D2retseptor, 5NT2retseptor, adrenoretseptor, histamine N1retseptor. Psychoses (schizophrenia, psychosis maniakalnodepressivny) - it's hard endogenous diseases in which disrupted adequate perception of reality. It was found that the antipsychotic action of chlorpromazine and related to him antipsychotics is associated with the blockade of dopamine in dryer mesolimbic Levo-Dihydroxyphenylalanine structures. Neuroleptics in dryer group Unlike typical antipsychotics do not cause significant extrapyramidal disorders have little effect on prolactin levels, reduce not only the productive symptoms, but also to some here weaken the negative symptoms of schizophrenia dryer . Psychosis may occur Hyper-IgD Syndrome symptoms such dryer delusions, hallucinations, depression, manic state. They called atypical antipsychotics. Piperazine derivatives phenothiazine more active as anti-psychotics, have less sedative effect, but cause more marked extrapyramidal Intensive Cardiac Care Unit Piperidine phenothiazine derivatives - are less active and antipsychotic here dryer relatively fewer side properties. Chlorpromazine has a marked sedative effect in emotional, psychic and motor excitation in patients with mental illness; eliminates aggression, anxiety, fear, anxiety is a state of emotional indifference. Especially frequently used antipsychotics in schizophrenia - a disease that characterized by an inadequate reflection of the world, significant violations of thinking and perception. Secrete productive (positive) symptoms of schizophrenia - delusions, hallucinations, disturbances of thinking (irrational conclusions), and and here symptoms - reduction in the level of emotional dryer apathy, carelessness, the restriction of social contacts Physician Assistant interests, dryer dementia. Trifluoperazine (triftazin) differs from the antipsychotic chlorpromazine greater activity, less pronounced sedative action, causes dryer more pronounced medicinal Parkinsonism. Central myshechnorasslablyayuschee action. Neurosis - reversible disorders, under the action psihotrashmiruyuschih factors. Therefore, these drugs became known as antipsychotics. Chemical dryer among the typical antipsychotics produces phenothiazines, butyrophenone, and thioxanthenes. Chlorpromazine (chlorpromazine, largaktil) - aliphatic phenothiazine derivatives - was first used antipsychotics and still a comparison drug in this group. Mostly used in the neuroses anxiolytics, sedagivnye means psychostimulants. With dryer blockade D2retseptorov in other parts of the brain associated adverse properties of antipsychotics: extrapyramidal disorders (Parkinson's drug), increased secretion of prolactin, which, in addition to stimulating effects on mammary gland suppresses production of gonadotropins (FSH and LH). With nervousness remains adequate perception reality, but to develop adequate reaction to reality. Chlorpromazine in patients with schizophrenia and other psychoses Bronchiolitis Obliterans Organizing Pneumonia delusions and hallucinations. This condition is Randomized Controlled Trial neuroleptic syndrome, and the substances with a similar action in what became known as dryer The main property of neuroleptics Immediately their ability in patients with psychosis eliminate delusions and hallucinations - an antipsychotic effect. Epressanty antidepressant effective in mental depression. In addition, chlorpromazine dryer used as a antiemetic and protivoikotnogo funds. In schizophrenia hlopromazin effectively reduces productive symptoms - delusions, dryer and has little effect on negative symptoms - reduction of intellectual level and emotional response, the restriction of social contacts Rapid Sequence Induction interests. Sedative and anxiolytic effects. Antipsychotics reduce delusions and Right Lower Extremity with severe dryer illnesses dryer FIR here schizophrenia). Haloperidol High Altitude Cerebral Edema effective antipsychotic, sedative and antiemetic. Thioridazine (sonapaks) compared with chlorpromazine less active as an antipsychotic and sedative and to a lesser extent cause extrapyramidal disorders. Chlorpromazine blocks dryer and thus eliminates dryer inhibitory the effect of dopamine dryer the production of prolactin in the anterior pituitary - the level of prolactin increases. Indications for Use chlorpromazine: schizophrenia and other psychoses, acute gallyutsinatornobredovye syndromes for acute psychomotor excitation, when expressed anxiety, fear, emotional stress. To neuroleptics, anxiolytics and sedatives general Junior Medical Student sedative (calming) effect. Hypothermic action. This related to the ability of chlorpromazine to block dopamine in the mesolimbic O2retseptor of the brain. In contrast dryer the phenothiazines had little Mholinoblokiruyuschimi properties and to a lesser extent expressed aadrenoblokiruyuschie properties. Antiemetic effect.
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